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Amenorrhea (Without Hirsutism) and Menopause

• Published: 1998
• Revised: March 2008
• Topic: Endocrine
• Scope: Laboratory testing
• Abstract: This guideline was developed to guide the appropriate laboratory testing to facilitate the investigation of causes of amenorrhea and to diagnosis menopause. It also describes the endocrine causes of amenorrhea.
• Target Population:
  • • Women with primary amenorrhea
  • • Girls with the lack of breast development by age 14 years, or by the lack of menses by age 16 in the
      presence of normal secondary sexual development, or by the lack of menses by 3 years after the larche
  • • Women with secondary amenorrhea (more than 6 months without menses after prior establishment of
      menses
• Exclusions: Pregnant women
• Working Group Membership: General practitioners, pathologists, endocrinologists, clinical biochemists, laboratory technologists, member of the public